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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LDLRAP1 All Species: 9.09
Human Site: S175 Identified Species: 22.22
UniProt: Q5SW96 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5SW96 NP_056442.2 308 33885 S175 A F E F W Q V S K E E K E K R
Chimpanzee Pan troglodytes XP_001145086 261 28665 F129 D K M H D K V F A Y I A Q S Q
Rhesus Macaque Macaca mulatta XP_001107620 308 33839 S175 A F E F W Q V S K E E K E K R
Dog Lupus familis XP_855049 309 33983 S175 A F E F W Q V S K E E K E K R
Cat Felis silvestris
Mouse Mus musculus Q8C142 308 33927 K175 F E F W Q V S K E E K E K R E
Rat Rattus norvegicus Q5PQS4 304 34267 R172 Q I A G M Q K R I Q D L E T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417736 307 33801 K175 F E F W Q A S K E E K E K R E
Frog Xenopus laevis Q67FQ3 309 34222 E176 E F W Q V S R E N K D K R E K
Zebra Danio Brachydanio rerio Q32PV0 300 33841 G167 V E T R K Q I G G L Q K R I Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122880 120 13239
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.4 97.7 93.8 N.A. 89.2 25 N.A. N.A. 73 71.1 23 N.A. N.A. 25.6 N.A. N.A.
Protein Similarity: 100 84.4 99 97 N.A. 95.1 44.4 N.A. N.A. 83.1 84.1 39.9 N.A. N.A. 33.4 N.A. N.A.
P-Site Identity: 100 6.6 100 100 N.A. 6.6 13.3 N.A. N.A. 6.6 13.3 13.3 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 46.6 26.6 N.A. N.A. 46.6 40 33.3 N.A. N.A. 0 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 30 0 10 0 0 10 0 0 10 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 10 0 0 0 0 0 20 0 0 0 0 % D
% Glu: 10 30 30 0 0 0 0 10 20 50 30 20 40 10 30 % E
% Phe: 20 40 20 30 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 10 10 0 0 0 0 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 10 0 10 0 10 0 0 10 0 % I
% Lys: 0 10 0 0 10 10 10 20 30 10 20 50 20 30 10 % K
% Leu: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % L
% Met: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 10 20 50 0 0 0 10 10 0 10 0 20 % Q
% Arg: 0 0 0 10 0 0 10 10 0 0 0 0 20 20 30 % R
% Ser: 0 0 0 0 0 10 20 30 0 0 0 0 0 10 0 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % T
% Val: 10 0 0 0 10 10 40 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 10 20 30 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _